| Year | Name | Class | First career start | GS | Record | Notes | Ref. |
| 2025 [Tennessee Volunteers football team|2025] | Joey Aguilar | Sr. | August 30th, 2025 | 12 | 8-4 | Transferred from UCLA after Nico Iamaleava transferred to UCLA; never played for the organization. Last played at Appalachian State in 2024 | - |
| 2024 | Nico Iamaleava | Fr. | | 13 | 10–3 | Transferred to UCLA | - |
| 2023 | Joe Milton III | 6th Year | | 12 | 8–4 | | - |
| 2023 | Nico Iamaleava | Fr. | January 1 | 1 | 1–0 | First career start on January 1, 2024, against #17 Iowa Hawkeyes football team|Iowa]. Citrus Bowl (January)|Citrus Bowl] MVP | - |
| 2022 | Joe Milton III | Sr. | | 2 | 2–0 | Orange Bowl MVP | - |
| 2022 | Hendon Hooker | 6th Year | | 11 | 9–2 | SEC Offensive Player of the Year, All-SEC football team|All-SEC] First Team, 5th in Heisman voting | - |
| 2021 | Joe Milton III | Jr. | September 2 | 2 | 1–1 | | - |
| 2021 | Hendon Hooker | Sr. | September 18 | 9 | 5–4 | | - |
| 2020 | Jarrett Guarantano | Sr. | | 7 | 2–5 | Transferred to Washington State | - |
| 2020 | Harrison Bailey | Fr. | December 5 | 3 | 1–2 | Transferred to UNLV | - |
| 2019 | Jarrett Guarantano | Jr. | | 7 | 4–3 | | - |
| 2019 | Brian Maurer | Fr. | October 6 | 4 | 2–2 | Transferred to Stephen F. Austin | - |
| 2019 | J. T. Shrout | Fr. | November 2 | 2 | 2–0 | Transferred to Colorado | - |
| 2018 | Jarrett Guarantano | So. | | 12 | 5–7 | | - |
| 2017 | Jarrett Guarantano | Fr. | October 14 | 6 | 1–5 | | - |
| 2017 | Quinten Dormady | Jr. | September 4 | 5 | 3–2 | Transferred to Houston | - |
| 2017 | Will McBride | Fr. | November 11 | 1 | 0–1 | Transferred to Lamar | - |
| 2016 | Joshua Dobbs | Sr. | | 13 | 9–4 | Music City Bowl MVP, All-SEC Second Team, Drafted 135th overall in the 2017 NFL draft by the Pittsburgh Steelers | - |
| 2015 | Joshua Dobbs | Jr. | | 13 | 9–4 | | - |
| 2014 | Justin Worley | Sr. | | 7 | 3–4 | | - |
| 2014 | Joshua Dobbs | So. | | 5 | 4–1 | Taxslayer Bowl MVP | - |
| 2014 | Nathan Peterman | So. | | 1 | 0–1 | Transferred to Pittsburgh. Drafted 171st overall in the 2017 NFL draft by the Buffalo Bills | - |
| 2013 | Justin Worley | Jr. | | 7 | 4–3 | | - |
| 2013 | Joshua Dobbs | Fr. | November 2 | 4 | 1–3 | | - |
| 2013 | Nathan Peterman | Fr. | September 21 | 1 | 0–1 | | - |
| 2012 | Tyler Bray | Jr. | | 12 | 5–7 | | - |
| 2011 | Tyler Bray | So. | | 7 | 4–3 | | - |
| 2011 | Justin Worley | Fr. | October 29 | 3 | 1–2 | | - |
| 2011 | Matt Simms | Sr. | | 2 | 0–2 | | - |
| 2010 | Matt Simms | Jr. | September 4 | 8 | 2–6 | | - |
| 2010 | Tyler Bray | Fr. | November 6 | 5 | 4–1 | | - |
| 2009 | Jonathan Crompton | Sr. | | 13 | 7–6 | | - |
| 2008 | Jonathan Crompton | Jr. | | 6 | 3–3 | | - |
| 2008 | Nick Stephens | Fr. | October 4 | 6 | 2–4 | | - |
| 2007 | Erik Ainge | Sr. | | 14 | 10–4 | Played 6 games under the influence of prescription painkillers | |
| 2006 | Erik Ainge | Jr. | | 12 | 9–3 | | - |
| 2006 | Jonathan Crompton | Fr. | November 11 | 1 | 0–1 | | - |
| 2005 | Erik Ainge | So. | | 5 | 4–1 | | - |
| 2005 | Rick Clausen | Sr. | | 6 | 1–5 | | - |
| 2004 | Erik Ainge | Fr. | October 2 | 6 | 4–2 | SEC Offensive Freshman of the Year | - |
| 2004 | Rick Clausen | Jr. | November 20 | 4 | 3–1 | Cotton Bowl Classic|Cotton Bowl Classic] Offensive MVP | - |
| 2004 | Brent Schaeffer | Fr. | September 5 | 3 | 3–0 | Transferred to the College of the Sequoias, later Ole Miss | - |
| 2003 | Casey Clausen | Sr. | | 13 | 10–3 | | - |
| 2002 | Casey Clausen | Jr. | | 11 | 7–4 | | - |
| 2002 | C.J. Leak | Jr. | October 12 | 1 | 0–1 | | - |
| 2002 | James Banks | Fr. | November 16 | 1 | 1–0 | | - |
| 2001 | Casey Clausen | So. | | 13 | 11–2 | Florida Citrus Bowl MVP | - |
| 2000 | Casey Clausen | Fr. | October 21 | 7 | 6–1 | | - |
| 2000 | A.J. Suggs | Fr. | September 16 | 4 | 1–3 | Transferred to Georgia Tech | - |
| 2000 | Joey Mathews | So. | September 2 | 1 | 1–0 | | - |
| 1999 | Tee Martin | Sr. | | 12 | 9–3 | All-SEC First Team | - |
| 1998 | Tee Martin | Jr. | September 5 | 13 | 13–0 | Led Tennessee to the 1998 National Championship. He broke the NCAA record for consecutive completions. | |
| 1997 | Peyton Manning | Sr. | | 13 | 11–2 | 1997 Heisman Trophy Runner Up. Davey O'Brien Award. Consensus All-American. SEC Player of the Year. All-SEC First Team. SEC Championship Game|SEC Championship] MVP. Florida Citrus Bowl MVP | - |
| 1996 | Peyton Manning | Jr. | | 12 | 10–2 | Third Team All-American. All-SEC Second Team. | - |
| 1995 | Peyton Manning | So. | | 12 | 11–1 | All-SEC First Team. | - |
| 1994 | Peyton Manning | Fr. | September 24 | 8 | 7–1 | SEC Freshman of the Year | - |
| 1994 | Branndon Stewart | Fr. | | | | Transferred to Texas A&M. | - |
| 1994 | Todd Helton | Jr. | September 10 | 3 | 1–2 | Played in 1994 until Peyton Manning took over primary QB duties. Went on to play Major League Baseball. | - |
| 1994 | Jerry Colquitt | Sr. | September 3 | 1 | 0–1 | | - |
| 1993 | Heath Shuler | Jr. | | 12 | 10–2 | 1993 Heisman Trophy Runner Up. SEC Player of the Year. All-SEC First Team. | |
| 1992 | Heath Shuler | So. | September 5 | 12 | 9–3 | Hall of Fame Bowl MVP | - |
| 1991 | Andy Kelly | Sr. | | 12 | 9–3 | | - |
| 1990 | Andy Kelly | Jr. | | 13 | 9–2–2 | Cotton Bowl MVP, All-SEC Second Team. | - |
| 1989 | Andy Kelly | So. | October 21 | 6 | 6–0 | | - |
| 1989 | Sterling Henton | So. | September 2 | 6 | 5–1 | | - |
| 1988 | Jeff Francis | Sr. | | 11 | 5–6 | | - |
| 1987 | Jeff Francis | Jr. | | 13 | 10–2–1 | | - |
| 1986 | Jeff Francis | So. | September 6 | 12 | 7–5 | Liberty Bowl MVP | - |
| 1985 | Daryl Dickey | Sr. | | 7 | 6–0–1 | Sugar Bowl MVP, became starter after Robinson injury – Team beat Miami in Sugar Bowl | - |
| 1985 | Tony Robinson | Sr. | | 5 | 4–1 | In 1985 was considered a Heisman candidate until season ending knee injury. | - |
| 1984 | Daryl Dickey | Jr. | September 22 | 1 | 0–0–1 | | - |
| 1984 | Tony Robinson | Jr. | September 1 | 11 | 7–4 | All-SEC First Team. | - |
| 1983 | Alan Cockrell | Jr. | | 12 | 9–3 | | - |
| 1982 | Alan Cockrell | So. | | 12 | 6–5–1 | | - |
| 1981 | Alan Cockrell | Fr. | September 19 | 2 | 2–0 | | - |
| 1981 | Steve Alatorre | Sr. | | 8 | 6–2 | Garden State Bowl MVP | - |
| 1981 | Jeff Olszewski | Sr. | | 2 | 0–2 | | - |
| 1980 | Steve Alatorre | Jr. | October 18 | 6 | 2–4 | | - |
| 1980 | Jeff Olszewski | Jr. | September 6 | 5 | 3–2 | | - |
| 1979 | Jimmy Streater | Sr. | | 12 | 7–5 | All-SEC. Nicknamed the "Sylva Streak" | - |
| 1978 | Jimmy Streater | Jr. | | 11 | 5–5–1 | | - |
| 1977 | Jimmy Streater | So. | September 10 | 9 | 4–5 | | - |
| 1977 | Pat Ryan | Sr. | October 8 | 2 | 0–2 | | - |
| 1976 | Randy Wallace | Sr. | | 11 | 6–5 | | - |
| 1975 | Randy Wallace | Jr. | September 14 | 12 | 7–5 | | - |
| 1974 | Condredge Holloway | Sr. | | 12 | 7–3–2 | | - |
| 1973 | Condredge Holloway | Jr. | | 11 | 7–4 | Holloway was one of the first African-American quarterbacks to receive national exposure. His nickname at Tennessee was the "Artful Dodger". | |
| 1972 | Condredge Holloway | So. | September 9 | 11 | 9–2 | | - |
| 1971 | Jim Maxwell | Sr. | October 30 | 6 | 6–0 | | - |
| 1971 | Phil Pierce | Sr. | October 2 | 4 | 3–1 | | - |
| 1971 | Dennis Chadwick | Jr. | September 18 | 2 | 1–1 | | - |
| Name | Years Started | Notability | References |
| Roe Campbell | 1921–1924 | Awarded the Porter Cup in 1922. Campbell attended Tusculum College before Tennessee, where he is a member of its sports Hall of Fame | |
| Joe Evans | 1920 | | |
| Willis McCabe | 1919 | Won The Porter Cup | |
| Buck Hatcher | 1916 | Led the Vols to their second SIAA title. The New York Times ranked him as the season's premier punter. | |
| Bill May | 1914–1915 | Led Tennessee to 1914 SIAA title, the first championship of any kind for the program. This season also featured Tennessee's first victory over Vanderbilt | |
| Red Rainey | 1913 | All-Southern. | |
| Rufus Branch | 1909–1912 | | |
| Chauncey Raulston | 1909 | | |
| J. C. Loucks | 1906–1908 | | |
| Walker Leach | 1905 | Captain of 1908 team. | - |
| T. R. Watkins | 1903–1904 | - | - |
| Sax Crawford | 1901–1902 | He coached Tennessee in 1904, scoring the first ever win over Alabama. | |
| J. G. Logan | 1900 | | |
| C. L. Bryan | 1899 | | |
| Strang Nicklin | 1897 | Nicklin transferred from UNC to UT in 1896. He was the first UT athlete to play major league baseball and the first to play in a World Series game. His paid baseball participation, together with playing baseball players who were not enrolled, occasioned the blacklisting of Tennessee by the SIAA in 1897. | |
| D. C. Chapman | 1896 | | |