James Roe

• James Roe (Irish politician), Member of Parliament for Cashel, 1832–1834
• James [Elphinstone Roe], Australian convict, educator and journalist
• James A. Roe, U.S. Representative from New York
• Jimmy Roe, American soccer player
• James M. Roe, American amateur astronomer
• James Roe (American football), Arena Football League player
• James Roe (rower), British adaptive rower
• James Roe (racing driver), Irish racing driver