James McGuire
James McGuire may refer to:
- James Washington Lonoikauoalii McGuire, Hawaiian courtier and dressmaker
- Deacon McGuire, American baseball player
- James G. Maguire, American Congressman
- James Kennedy McGuire, American politician, mayor of Syracuse, New York
- James McGuire (Irish politician), Irish Cumann na nGaedhael politician
- James McGuire (soccer), president of the United States Soccer Federation
- James McGuire (footballer), English footballer
- James McGuire (VC), Irish recipient of the Victoria Cross
- James McGuire (railways), commissioner of railways in South Australia
- Jim McGuire (baseball coach), American college baseball coach
- Jim McGuire (shortstop), American baseball shortstop
- Jim McGuire (American football), American football coach
- Jimmy McGuire, member of the Jeopardy! Clue Crew