Jelleine


Jelleine is a family of peptides, isolated from the royal jelly of Apis mellifera iberiensis, a subspecies of the honey bee. This new family has the potential to be used in the development of new drugs.

Discovery

Jelleines were first isolated in 2004 by the research group of Professor Mario Sergio Palma at São Paulo State University, Brazil. First, he collected royal jelly from a group of honey bee larvae and purified the results by reverse phase, high-performance liquid chromatography. This purified royal jelly showed antimicrobial activity against different bacteria. So far, four peptides have been found in this family, each one containing the carboxamide C-terminal.

Medical research

Jelleine exhibits antimicrobial activity against S. epidermidis.