James Prendergast

• James Prendergast (Canadian politician), judge and politician in western Canada
• James Prendergast (judge), third Chief Justice of New Zealand
• James F. Prendergast, member of the Pennsylvania House of Representatives
• James Luke Prendergast, merchant and political figure in Newfoundland
• James Prendergast (pioneer), early Chautauqua County settler, Jamestown, New York was named in his honour