James Mercer

• James Mercer (judge), American jurist, Virginia delegate to Continental Congress
• James Mercer (Australian politician), New South Wales politician
• James Mercer (mathematician), English mathematician
• James Mercer (musician), American guitarist and musician
• Bert Mercer, New Zealand aviator
• James Mercer (diplomat), former Ghanaian ambassador to Israel and chairman of Ghana Airways
• James Mercer (poet), Scottish soldier and poet