James Lowther
James Lowther may refer to:
- Sir James Lowther, 4th Baronet, Member of Parliament for Appleby, Carlisle, and Cumberland
- James Lowther, 1st Earl of Lonsdale, electoral magnate in northern England, Member of Parliament for Cockermouth, Cumberland, Haslemere and Westmorland
- Colonel James Lowther (1753–1837), Member of Parliament for Appleby, Haslemere and Westmorland
- James Lowther (politician, born 1840), Tory politician and sportsman, sometime Chief Secretary for Ireland, Member of Parliament for the Isle of Thanet, Lincolnshire North, and York
- James Lowther, 1st Viscount Ullswater, Conservative politician and Speaker of the House of Commons
- James Lowther, 7th Earl of Lonsdale, British peer