James Hepburn
James Hepburn may refer to:
- James Hepburn , Bishop of Moray
- James Hepburn, 4th Earl of Bothwell, Scottish ruler, Duke of Orkney, the third husband of Mary, Queen of Scots
- Bonaventure Hepburn, Scottish orientalist
- James Hepburn Campbell, American politician and diplomat
- James Curtis Hepburn, American missionary
- James de Congalton Hepburn, Canadian MPP
- Jamie Hepburn, Scottish politician
- James Hepburn , English ornithologist
- Jock Hepburn, birth name James, Scottish footballer
- James Hepburn , golfer from Scotland