James Gamble
James Gamble may refer to:
- James Gamble , U.S.-based Irish soapmaker and industrialist; co-founder of Procter & Gamble Company
- James Gamble , U.S. Representative from Pennsylvania
- James Gamble , Piedmont resident, and builder of the first telegraph in California
- James Sykes Gamble, English botanist
- James Fulton Gamble, Northern Irish politician
- James Gamble, Canadian co-conspirator responsible for the Halifax mass shooting plot