James Clayton
James or Jim Clayton may refer to:
- James Clayton (priest), English Roman Catholic priest
- James Clayton (engineer), British railway locomotive engineer
- Gordon Clayton (footballer, [born 1910)], English footballer
- Jim Clayton (rower), New Zealand rower
- Jim Clayton (businessman), American entrepreneur who founded Clayton Homes
- Jim Clayton (musician), Canadian jazz musician
- James Clayton (baritone), Australian baritone, see 12th [Helpmann Awards]
- Clayton Chitty, aka Clayton James, Canadian actor and model