Issa
- Catawba people
- El-Issa family
- ISSE (disambiguation)
- Information Systems Security Association
- Instituto Superior de Secretariado y Administracion (ISSA)
- International Sailing Schools Association
- International Sanamahism Students' Association, Kangleipak
- International Social Security Association
- International Sports Sciences Association
- International Strategic Studies Association
- Interscholastic Sailing Association
- Irish Seed Savers Association
- Isa (disambiguation)
- Isa (river)
- Islamic Solidarity Sports Association
- Issa (Belgariad)
- Issa (Lesbos)
- Issa (clan)
- Issa (inhabited locality)
- Issa (moth)
- Issa (mythology)
- Issa (name)
- Issa (polis)
- Issa Album
- Issa, Ghana
- Issa, Penza Oblast
- Issei
- Jane Siberry
- Jesus in Islam
- Kobayashi Issa
- Luttif Afif
- Sports Association for Adelaide Schools