Isobutyryl chloride

Isobutyryl chloride is the organic compound with the formula. A colorless liquid, it the simplest branched-chain acyl chloride. It is prepared by chlorination of isobutyric acid.

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As an ordinary acid chloride, isobutyryl chloride is the subject of many reported transformations. Dehydrohalogenation of isobutyryl chloride with triethylamine gives 2,2,4,4-tetramethylcyclobutanedione. Treatment of isobutyryl chloride with hydrogen fluoride gives the acid fluoride.