Isobutylamine

Isobutylamine is an organic chemical compound with the formula ₂CHCH₂NH₂, and occurs as a colorless liquid. Isobutylamine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and tert-butylamine. It is the decarboxylated form of the amino acid valine, and the product of the metabolism thereof by the enzyme valine decarboxylase.

Production

Isobutylamine can be obtained by reaction of isobutanol with ammonia in presence of a catalyst:
Isobutylamine can also be produced from the reaction of Isobutyl chloride with ammonia:
A alternative method of producing Isobutylamine is the decarboxylation of Valine with the enzyme Valine decarboxylase or the thermal decarboxylation:

Uses

Isobutylamine is an odorant binding to TAAR3 in mice and can trigger sexual behaviour in male mice dependent on the cluster of TAAR2 through TAAR9.