About 30% of those received intravenous iodixanol injection has warmth, pain, or discomfort at the site of the injection. Other adverse effects include: taste perversion, nausea, and headache.
Iodixanol is also the active ingredient in a number of 'cushion' products used during the centrifugation of stallion semen. It is layeredunderneath the extended stallion semen allowing for a higher g force to be used with less sperm damage and better recovery rates. Post centrifugation the supernatant above and the cushion below is removed, leaving a concentrated sperm pellet in the conical tube.