Intradialytic parenteral nutrition
Intradialytic parenteral nutrition is a nutritional support therapy for people on hemodialysis who have a difficult time maintaining adequate nutrition. It is administered directly into the bloodstream of patients with chronic kidney disease in an effort to decrease the associated morbidity and mortality experienced in patients with kidney failure. IDPN contains protein, carbohydrates, and fats in an attempt to meet a patient's weekly nutritional needs. Solutions can be individualized for each patient based on weight, needs, medical history and enteral intake.
History
Prior to 1990, traditional therapies for dialysis patients, such as liberalized diet and oral supplements, led to protein and/or calorie malnutrition.Efforts to supplement nutritional intake by providing nutrients during the dialysis procedure were attempted. As a result, IDPN became an established therapy to replete malnourished CKD-5 dialysis patients in the early 1990s. Generally the patients received a set formulation containing standard amounts of dextrose, amino acids and lipids regardless of the patient's weight, dialysis time, and complicating co-morbid conditions.