SBI Route 107 originally ran from Pike Station to Griggsville. In 1935, all of the routessouth of Pittsfield was changed to U.S. 54, leaving the portion between Pittsfield and Griggsville as Illinois 107. In 1964 the northern extension to Mount Sterling was added. In 1992, U.S. 54 replaced Illinois 107 north to the new U.S. Route 36freeway, which then became Interstate 72. As a result, Illinois 107 and U.S. 54 now terminate at the same interchange.