Identification of Conserved Water Sites in Protein Structures for Drug Design
Identification of Conserved Water Sites in Protein Structures for Drug Design is a scholarly work by Stanislav Gobec and Dusanka Janezic, published in 2017 in ''Journal of Chemical Information and Modeling''. The main subjects of the publication include identification, protein structure prediction, drug discovery, ribosome, protein design, chemistry, drug, and computational biology. The authors developed the ProBiS H2O approach based on the previously developed ProBiS algorithm, which enables identification of conserved water sites in proteins using experimental protein structures from the PDB or a set of custom protein structures available to the user.