IHS
- Christogram
- Dictaphone
- HSL color space
- IBM HTTP Server
- IHS Markit
- In hoc signo
- Independence High School (Arizona)
- Independence High School (San Jose, California)
- Indian Health Service
- Indiana Historical Society
- Institute for Housing and Urban Development Studies
- Institute for Humane Studies
- Institute for Humanist Studies
- Integrated Household Survey
- Interlake High School
- International Headache Society
- International Horn Society
- Interstate Highway System
- Ipswich Historical Society
- Irondequoit High School
- Irvine High School
- Issaquah High School
- Ithaca High School (Ithaca, New York)
- The Indian High School, Dubai