IDC
- Collar (group)
- Department of Economic Development (South Africa)
- Dilated cardiomyopathy
- I Don't Care (Ed Sheeran and Justin Bieber song)
- IDC (musician)
- Ideographic Description Characters
- Imperial Defence College
- Independent Democratic Conference
- Indirect costs
- Industrial Design Centre
- Industrial Development Certificate
- Industrial Development Corporation
- Indwelling catheter
- Infiltrating ductal carcinoma
- Information Dominance Corps
- Institut de Cognitique
- Institute of Democracy and Cooperation
- Institute of Design and Construction
- Insulation-displacement connector
- Inter-domain Controller protocol
- InterDigital Communications
- Interactive Data Corporation
- Interdisciplinary Center Herzliya
- Interdnestrcom
- International Data Corporation
- International Detention Coalition
- Internet data center
- Internet slang
- Invensys
- Islands District Council
- List of acronyms in oil and gas exploration and production
- Paris Institute of Comparative Law
- Time to Go Home
- United States Marine Air-Ground Task Force Reconnaissance