ICAN
- 1-Isocyano-5-aminonaphthalene
- I Can (disambiguation)
- ICAN-II (spacecraft)
- ICANN
- Icahn (disambiguation)
- Icán River
- Informed Consent Action Network
- Institute of Chartered Accountants of Namibia
- Institute of Chartered Accountants of Nepal
- Institute of Chartered Accountants of Nigeria
- Interim Capability for Airborne Networking
- International Campaign to Abolish Nuclear Weapons
- International Children Assistance Network
- International Christian Academy of Nagoya
- International Code of Area Nomenclature
- International Commission for Air Navigation
- JCAN
- Nationalist Canarian Initiative