ICU
- After Party (Adore Delano album)
- Dancing with the Devil... the Art of Starting Over
- I See You (disambiguation)
- I.C.U. (film)
- ICU (song)
- ICU Medical
- Imperial College Union
- Industrial and Commercial Workers' Union
- Industrial and Commercial Workers' Union (Ghana)
- Information and Communications University
- Inner City Unit
- Intensive care unit
- International Cheer Union
- International Christian University
- International Christian University – Kyiv
- International Clearing Union
- International Components for Unicode
- Internationalist Communist Union
- Intersection capacity utilization
- Investment Capital Ukraine
- Irish Chess Union
- Islamic Courts Union
- Istanbul Commerce University
- List of Internet top-level domains
- Punisher (album)
- The Wait Is Over
- What I Didn't Tell You