Hughes House
- Charles Evans Hughes House
- Daniel H. Hughes House
- David and M. Maria Hughes House
- Dr. Herbert H. Hughes House
- Elzey Hughes House
- Hughes House (Benton, Louisiana)
- Hughes House (Elk Rapids, Michigan)
- Hughes House (Jefferson, Pennsylvania)
- Hughes Manor
- Hughes-Cunningham House
- Hughes–Clark House
- J. G. Hughes House
- J. Willis Hughes House
- Langston Hughes House
- Martin Hughes House
- Patrick Hughes House
- Thomas H. Hughes House
- University of St. Thomas (Texas)
- W.J. Hughes Business House
- Wood–Hughes House