Hospital de Santa MariaHospital de Santa Maria is a public Central Hospital serving the Greater Lisbon area as part of the Northern Lisbon University Hospital Centre, a State-owned enterprise. Santa Maria is the largest hospital in Portugal.HistorySaint Mary's Hospital is located in the Cidade Universitária, the main campus of the University of Lisbon and ISCTE – University Institute of Lisbon, within the civil parish of Alvalade. Designed by German architect Hermann Distel, it was built from 1940 to 1953, meant as a new University Hospital housing the Faculty of Medicine of the University of Lisbon.