Homology-based loop modeling yields more complete crystallographic protein structures
Homology-based loop modeling yields more complete crystallographic protein structures is a scholarly work by Maarten Hekkelman, Robbie P. Joosten, Anastassis Perrakis, and Bart van Beusekom, published in 2018 in ''IUCrJ''. The main subjects of the publication include data mining, crystallography, protein superfamily, software pipeline, Protein Data Bank, flexibility, model building, computational biology, Loop modeling, homology modeling, computer science, protein structure database, bioinformatics, Protein Data Bank, protein structure, protein structure prediction, metabolic engineering, software, and structural bioinformatics. The paper presents algorithms that identify regions missing in a certain model but present in homologous structures in the Protein Data Bank (PDB), and `graft' these regions of interest.