Homoisocitric acid
Homoisocitric acid, with the systematic name 1-hydroxy-1,2,4-butanetricarboxylic acid is a positional isomer of homocitric acid, which is 2-hydroxy-1,2,4-butanetricarboxylic acid. The stereoisomer found in nature, the form, is an intermediate in the α-aminoadipate pathway of lysine biosynthesis where it is produced by homocitrate synthase:
It is a substrate for homoaconitate hydratase.
The compound is also acted on by homoisocitrate dehydrogenase to give 2-oxoadipic acid:
Homoisocitrate is an anion, salt, or ester of homoisocitric acid.