Holmes House
- Benjamin Holmes House
- Dr. Job Holmes House
- Francis H. Holmes House
- Gustavus Holmes House
- Holmes (disambiguation)
- Holmes Cottage
- Holmes House, South Duffield
- Holmes on Homes
- Holmes-Crafts Homestead
- Holmes-Shannon House
- Holmes–Hendrickson House
- Holmes–Tallman House
- John Holmes House
- Joseph Holmes House
- National Register of Historic Places listings in Clackamas County, Oregon
- National Register of Historic Places listings in Clatsop County, Oregon
- National Register of Historic Places listings in Cumberland County, North Carolina
- National Register of Historic Places listings in Iron County, Michigan
- National Register of Historic Places listings in Lake County, Illinois
- National Register of Historic Places listings in Pennington County, South Dakota
- National Register of Historic Places listings in Pike County, Mississippi
- Oliver Wendell Holmes House
- Perrigo-Holmes House
- Samuel Holmes House
- Sedberry-Holmes House
- Sen. John Holmes House
- William L. Holmes House