Henry Shirley

• Henry Shirley (dramatist), English dramatist, murdered by Sir Edward Bishopp, 2nd Baronet
• Henry Shirley, 3rd Earl Ferrers, English nobleman and lunatic
• Henry Shirley (diplomat) on List of ambassadors of the United Kingdom to Russia
• Arthur Shirley, Australian actor, writer, producer and director
• Henry G. Shirley, commissioner of the Virginia Department of Highways
• Sir Henry Shirley, 2nd Baronet, landowner and local politician