Hematologic disease
Hematologic diseases are disorders which primarily affect the blood and blood-forming organs. Hematologic diseases include rare genetic disorders, anemia, HIV, sickle cell disease and complications from chemotherapy or transfusions.
Myeloid
Hemoglobinopathies- * Sickle cell disease
- * Thalassemia
- * MethemoglobinemiaAnemias
- * Iron-deficiency anemia
- * Megaloblastic anemia
- ** Vitamin B12 deficiency
- *** Pernicious anemia
- ** Folate deficiency
- * Hemolytic anemias
- ** Genetic disorders of RBC membrane
- *** Hereditary spherocytosis
- *** Hereditary elliptocytosis
- *** Congenital dyserythropoietic anemia
- ** Genetic disorders of RBC metabolism
- *** Glucose-6-phosphate dehydrogenase deficiency
- *** Pyruvate kinase deficiency
- ** Immune mediated hemolytic anemia
- *** Autoimmune [hemolytic anemia]
- **** Warm antibody autoimmune hemolytic anemia
- ***** Idiopathic
- ***** Systemic lupus erythematosus
- ***** Evans syndrome
- **** Cold autoimmune hemolytic anemia
- ***** Cold agglutinin disease
- ***** Paroxysmal cold hemoglobinuria
- ***** Infectious mononucleosis
- *** Alloimmune hemolytic anemia
- **** Hemolytic disease of the newborn
- ***** Rh disease
- ***** ABO hemolytic disease of the newborn
- ***** Anti-Kell hemolytic disease of the newborn
- ***** Rhesus c hemolytic disease of the newborn
- ***** Rhesus E hemolytic disease of the newborn
- ***** Other blood group incompatibility
- *** Drug induced immune mediated hemolytic anemia
- **** Penicillin
- **** Methyldopa
- ** Hemoglobinopathies
- ** Paroxysmal nocturnal hemoglobinuria
- ** Direct physical damage to RBCs
- *** Microangiopathic hemolytic anemia
- *** Secondary to artificial heart valve
- * Aplastic anemia
- ** Fanconi anemia
- ** Diamond–Blackfan anemia
- ** Acquired pure red cell aplasiaDecreased numbers of cells
- * Myelodysplastic syndrome
- * Myelofibrosis
- * Neutropenia
- * Agranulocytosis
- * Glanzmann's thrombasthenia
- * Thrombocytopenia
- ** Idiopathic thrombocytopenic purpura
- ** Thrombotic thrombocytopenic purpura
- ** Heparin-induced thrombocytopenia Myeloproliferative disorders
- * Polycythemia vera
- * Erythrocytosis
- * Leukocytosis
- * Thrombocytosis
- * Myeloproliferative disorder
- * Transient myeloproliferative diseaseCoagulopathies
- * Thrombocytosis
- * Recurrent thrombosis
- * Disseminated intravascular coagulation
- * Disorders of clotting proteins
- ** Hemophilia
- *** Hemophilia A
- *** Hemophilia B
- *** Hemophilia C
- ** Von Willebrand disease
- ** Disseminated intravascular coagulation
- ** Protein S deficiency
- ** Antiphospholipid syndrome
- * Disorders of platelets
- ** Thrombocytopenia
- ** Glanzmann's thrombasthenia
- ** Wiskott–Aldrich syndrome
Hematological malignancies
Hematological malignancies- * Lymphomas
- ** Hodgkin's disease
- ** Non-Hodgkin's lymphoma
- *** Burkitt's lymphoma
- *** Anaplastic large cell lymphoma
- *** Splenic marginal zone lymphoma
- *** Hepatosplenic T-cell lymphoma
- *** Angioimmunoblastic T-cell lymphoma
- * Myelomas
- ** Multiple myeloma
- ** Waldenström macroglobulinemia
- ** Plasmacytoma
- * Leukemias increased WBC
- ** Acute lymphocytic leukemia
- ** Chronic lymphocytic leukemia
- ** Acute myelogenous leukemia
- ** Acute megakaryoblastic leukemia, a sub-type of acute myelogenous leukemia
- ** Chronic Idiopathic Myelofibrosis
- ** Chronic myelogenous leukemia
- ** T-cell prolymphocytic leukemia
- ** B-cell prolymphocytic leukemia
- ** Chronic neutrophilic leukemia
- ** Hairy cell leukemia
- ** T-cell large granular lymphocyte leukemia
- ** Aggressive NK-cell leukemia
Miscellaneous
- Hemochromatosis
- Asplenia
- Hypersplenism
- * Gaucher's disease
- Monoclonal gammopathy of undetermined significance
- Hemophagocytic lymphohistiocytosis
- Tempi syndrome