Lability


Lability refers to the degree that something is likely to undergo change. It is the opposite of stability.

Biochemistry

In reference to biochemistry, this is an important concept as far as kinetics is concerned in metalloproteins. This can allow for the rapid synthesis and degradation of substrates in biological systems.

Biology

Cells

Labile cells refer to cells that constantly divide by entering and remaining in the cell cycle. These are contrasted with "stable cells" and "permanent cells".
An important example of this is in the epithelium of the cornea, where cells divide at the basal level and move upwards, and the topmost cells die and fall off.

Proteins

In medicine, the term "labile" means susceptible to alteration or destruction. For example, a heat-labile protein is one that can be changed or destroyed at high temperatures.
The opposite of labile in this context is "stable".

Soils

Compounds or materials that are easily transformed are termed labile. For example, labile phosphate is that fraction of soil phosphate that is readily transformed into soluble or plant-available phosphate. Labile organic matter is the soil organic matter that is easily decomposed by microorganisms.

Chemistry

The term is used to describe a transient chemical species. As a general example, if a molecule exists in a particular conformation for a short lifetime, before adopting a lower energy conformation, the former molecular structure is said to have "high lability". The term is sometimes also used in reference to reactivity – for example, a complex that quickly reaches equilibrium in solution is said to be labile. Another common example is the cis effect in organometallic chemistry, which is the labilization of CO ligands in the cis position of octahedral transition metal complexes.