HaloprogesteroneHaloprogesterone, sold under the brand name Prohalone, is a progestin medication which was previously marketed by Ayerst but is now no longer available.ChemistryHaloprogesterone, also known as 6α-fluoro-17α-bromoprogesterone or as 6α-fluoro-17α-bromopregn-4-ene-3,20-dione, is a synthetic pregnane steroid and a halogenated derivative of progesterone. It is specifically a derivative of 17α-bromoprogesterone and is similar structurally to medrogestone, medroxyprogesterone acetate, and various other progestins derived from progesterone.SynthesisChemical syntheses of haloprogesterone have been published.HistoryHaloprogesterone was synthesized in 1960 and was introduced for medical use by 1961.Society and cultureGeneric namesHaloprogesterone is the generic name of the drug and its and.Brand namesHaloprogesterone was marketed under the brand name Prohalone.