HSM
- Data Facility Storage Management Subsystem (MVS)
- HMS (disambiguation)
- HSM (company)
- Harakat al-Shabaab Mujahedeen
- Hardware security module
- Hepatosplenomegaly
- Hierarchical state machine
- Hierarchical storage management
- High School Musical (disambiguation)
- Historic Sites and Monuments in Antarctica
- Hollandsche IJzeren Spoorweg-Maatschappij
- Holy Spirit Movement
- Horsham Airport
- Humanitarian Service Medal
- MVS
- Ultrasonic motor