HPS
- 3-hexulose-6-phosphate synthase
- Croatian Mountaineering Association
- Croatian Popular Party (disambiguation)
- HP (disambiguation)
- HPS stain
- HPSS (disambiguation)
- Habib Public School
- Halepaghen Grammar School
- Hamtramck Public Schools
- Handley Page HPS
- Hantavirus pulmonary syndrome
- Harris platelet syndrome
- Hastings Public Schools (Nebraska)
- Hawai'i Sign Language
- Hawkes Pocket Scores
- Hazelwood Power Station
- Headlands Preparatory School
- Health Physics Society
- Health Protection Scotland
- Heart Protection Study
- Heartland Payment Systems
- Helsingin Palloseura
- Hermansky–Pudlak syndrome
- High-pressure sodium
- Highline Public Schools
- Hindawi Programming System
- History and philosophy of science
- Humanist Party of Switzerland
- Hundred Peaks Section
- Hyderabad Public School
- Hydraulic power steering
- Hydroelectric power station
- Ilford HPS
- List of airline codes (H)
- Protection Force of Sinjar