HLA-B44HLA-B44 is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B.B44 is a split antigen of the broad antigen B12, and is a sister type of B45.SerotypeAllelesDiseaseHLA-B44 increases recurrent sinopulmonary infections. Protective effects: HLA-B44 appears to be protective against autoimmune lymphoproliferative syndrome in patients with C95 defect. B44 may be a cofactor in ankylosing spondylitis