HGS
- HGS (electronic toll collection)
- HGS (gene)
- Halifax Grammar School
- Hampstead Garden Suburb
- Handsworth Grammar School
- Hastings Airport (Sierra Leone)
- Hastings railway station
- Head Gear System
- Head-up guidance system
- Heckmondwike Grammar School
- Hervormd Gereformeerde Staatspartij
- Human Genome Sciences
- HydroGeoSphere
- Mercury sulfide
- The Harvey Grammar School