Group II pyridoxal-dependent decarboxylases
In molecular biology, group II pyridoxal-dependent decarboxylases are a family of enzymes including aromatic-L-amino-acid decarboxylase that catalyse the decarboxylation of tryptophan to tryptamine, tyrosine decarboxylase that converts tyrosine into tyramine and histidine decarboxylase that catalyses the decarboxylation of histidine to histamine.
Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence: group II includes glutamate, histidine, tyrosine, and aromatic-L-amino-acid decarboxylases.