Great Western
- Chicago Great Western Railway
- GWR 3031 Class
- GWR Iron Duke class
- GWR Iron Duke class
- Great West (disambiguation)
- Great Western Air Ambulance Charity
- Great Western Ambulance Service
- Great Western Arms Company
- Great Western Bank (disambiguation)
- Great Western Brewing Company
- Great Western Building
- Great Western Business and Normal College
- Great Western Cattle Trail
- Great Western Cities
- Great Western Combination
- Great Western Divide
- Great Western Garment Co.
- Great Western Holdings
- Great Western Hospital
- Great Western Hospitals NHS Foundation Trust
- Great Western Hotel (disambiguation)
- Great Western Lacrosse League
- Great Western Loop
- Great Western Main Line
- Great Western Mine
- Great Western Mine (Lake County, California)
- Great Western Mountain
- Great Western Railroad (Illinois)
- Great Western Railroad (Ohio)
- Great Western Railway
- Great Western Railway (Ontario)
- Great Western Railway (Saskatchewan)
- Great Western Railway (train operating company)
- Great Western Railway of Colorado
- Great Western Road (disambiguation)
- Great Western Schoolhouse
- Great Western Steam Laundry
- Great Western Sugar Company
- Great Western Tiers
- Great Western Trail
- Great Western Trail (board game)
- Great Western Turnpike
- Great Western Valkyrie
- Great Western Woodlands
- Great Western railway station
- Great Western, Victoria
- List of GWR 4073 Class locomotives
- PS Great Western (1864)
- SS Great Western
- Sarah A. Bowman
- TSS Great Western (1901)
- TSS Great Western (1933)
- The Great Western
- The Great Western Chorus of Bristol
- The Great Western Cotton Factory
- USS Great Western