Goblet cell carcinoid

The goblet cell carcinoid is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.

Sign and symptoms

GCCs may present as appendicitis.

Diagnosis

GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes goblet cell-like cells, and neuroendocrine-type nuclear chromatin.

Prognosis

GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.

Treatment

GCCs are treated with surgery.