Glycine methyl ester hydrochloride


Glycine methyl ester hydrochloride is the organic compound with the formula Cl. A white, water-soluble solid, it is the hydrochloride of the methyl ester of the amino acid glycine.

Synthesis and reactions

Glycine methyl ester hydrochloride can be prepared by treatment of glycine with 2 equivalents of trimethylsilyl chloride, followed by the addition of methanol.
Upon treatment with base, the salt converts to glycine methyl ester.
Glycine methyl ester are not shelf-stable, tending to polymerize when stored at room temperature or convert to diketopiperazine. The hydrochloride is shelf-stable.