George Willoughby

• George Willoughby (activist), American Quaker activist
• Sir George Willoughby (MP), English MP for Marlborough, 1685–1695
• George Willoughby, 7th Baron Willoughby of Parham, English peer
• George Willoughby, 17th Baron Willoughby of Parham, English peer
• George Willoughby (East India Company officer), British soldier in India
• George Willoughby (theatre entrepreneur), English theatre entrepreneur
• George Willoughby (producer), Norwegian film producer