George Hume
George Hume may refer to:
- Sir George Hume, 1st Baronet, Scottish-Irish baronet
- George Hume (surveyor), Scottish-American surveyor and colonial official
- George Steuart Hume, Maryland physician and landowner
- George Hume Macartney, born George Hume, Irish politician
- George Hume (cricketer), English cricketer
- George Hume (politician), British politician and leader of the London County Council
- George Sherwood Hume, Canadian geologist
- Basil Hume, born George Haliburton Hume, English Catholic cardinal
- George H. Hume, American heir, businessman and philanthropist