Gem-associated protein 7

Gem-associated protein 7 is a protein that in humans is encoded by the GEMIN7 gene. The gem-associated proteins are those found in the gems of Cajal bodies.

Function

The protein encoded by this gene is a component of the core SMN complex, which is required for pre-mRNA splicing in the nucleus. The encoded protein is found in the nucleoplasm, in nuclear "gems", and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.

Interactions

Gem-associated protein 7 has been shown to interact with SMN1 and Gem-associated protein 6.