GPR143
G-protein coupled receptor 143, also known as Ocular albinism type 1 in humans, is a conserved integral membrane protein with seven transmembrane domains and similarities with G protein-coupled receptors that is expressed in the eye and epidermal melanocytes. This protein encoded by the GPR143 gene, whose variants can lead to Ocular [albinism type 1].
The GPR143 gene is regulated by the Microphthalmia-associated transcription factor.
L-DOPA is an endogenous ligand for OA1.