GPO
- General Pico Airport
- General Post Office
- General Post Office (disambiguation)
- General Post Office, Dublin
- General Purpose Outlet
- General-purpose input/output
- Generalplan Ost
- Giant Pacific Octopus
- Gospel Oak railway station
- Government Pharmaceutical Organization
- Government Press Office (Israel)
- Green Party of Ontario
- Group Policy Object
- Group Purchasing Organization
- Group purchasing organization
- Guam Premier Outlets
- Indore G.P.O.
- Lieutenant
- Social Security Government Pension Offset
- United States Government Publishing Office