GPC
- GNU Pascal
- GPC (Mystery Science Theater 3000)
- GPC Biotech
- GPC Sport
- Geiriadur Prifysgol Cymru
- Gel permeation chromatography
- Gene Polisseni Center
- General People's Congress (disambiguation)
- General Polygon Clipper
- Generalized polynomial chaos
- Genuine Parts Company
- George Pearson Centre
- Georgia Perimeter College
- Giant papillary conjunctivitis
- Gigaparsec
- Global Plant Clinic
- Global Pound Conference
- Global Privacy Control
- Global Product Classification
- Glycerophosphorylcholine
- Glycophorin C
- Glypican
- Goa People's Congress
- Goldwyn Pictures
- Government Procurement Card
- Government Purchase Card
- Green Party of Canada
- Group of Cameroonian Progressives
- Putnam County Airport
- Remington GPC