Functionalized D-form self-assembling peptide hydrogels for bone regeneration
Functionalized D-form self-assembling peptide hydrogels for bone regeneration is a scholarly work, published in 2016 in ''Drug Design, Development and Therapy''. The main subjects of the publication include chemistry, hydrogel, biomedical engineering, self-healing hydrogel, Self-assembling peptide, peptide, regeneration, and self-assembly. The authors report on the structural features (eg, Congo red staining, circular dichroism spectroscopy, transmission electron microscopy, and rheometry assays) and osteogenic ability of d-RADA16-RGD peptide hydrogels (with or without basic fibroblast growth factor) due to the better stability of peptide bonds formed by these peptides compared with those formed by l-form peptides, and use them to fill the femoral condyle defect of Sprague Dawley rat model.