Frank Pearce

• Frank Pearce (footballer), Australian rules footballer
• Frank Pearce (businessman), American video game executive
• Frank Pearce (cricketer), Jamaican cricketer
• Frank Pearce (1870s pitcher), American baseball pitcher for the 1876 Louisville Grays
• Frank Pearce (1930s pitcher), American baseball pitcher for the 1933–35 Philadelphia Phillies
• Frank Pearce, tennis player in 1905 [Wimbledon Championships – Men's Singles]