Francis II
Francis II may refer to:
- Francis II, Duke of Brittany
- Francesco II Gonzaga, Marquess of Mantua, ruler of the Italian city of Mantua
- Francis II of France, king of France
- Francis II, Duke of Lorraine, son of Charles III, Duke of Lorraine, and Claude of Valois
- Francesco II d'Este, Duke of Modena
- Francis II Rákóczi, Prince of Transylvania
- Francis II, Holy Roman Emperor, last Holy Roman Emperor and first Austrian emperor
- Francis II of the Two Sicilies, last king of the Two Sicilies
- Franz, Duke of Bavaria, called "Francis II" by supporters of the Jacobite claim to the thrones of England, Scotland, Ireland, and France
- Francis II, Duke of Saxe-Lauenburg, third son of Francis I of Saxe-Lauenburg and Sybille of Saxe-Freiberg