Frank Holmes
Frank Holmes may refer to:
- Sir Frank Holmes , New Zealand economist
- Frank Holmes , British geologist
- Frank E. Holmes, chief executive and chief investment officer at U.S. Global Investors
- Frank Holmes , American track and field athlete
- Frank J. Holmes, American painter
- Frank Holmes , producer and director of Seaport of the Prairies
- Frank Holmes , Australian rules footballer
- Frankie Holmes, a co-host and subject of the documentary television series ''Dopesick Nation''