Francis Duffy
Francis or Frank Duffy may refer to:
- Francis Duffy (bishop), Roman Catholic Bishop of Ardagh and Clonmacnoise
- Francis Clyde Duffy, Lieutenant Governor of North Dakota
- Francis Noel Duffy, Irish Green Party politician for Dublin South-West
- Francis P. Duffy, Roman Catholic priest in the U.S.
- Frank Duffy (architect), British architect
- Frank Duffy (baseball), Major League Baseball player
- Frank Duffy (curler), Scottish wheelchair curler
- Frank Duffy (equestrian), American equestrian
- Frank Duffy (labor leader), American labor leader and secretary-general
- Sir Frank Gavan Duffy, Australian judge