Francesco Mancini

• Francesco Mancini (footballer, born 1968), Italian footballer
• Francesco Mancini (footballer, born 1990), Italian footballer
• Francesco Mancini (1679–1758), Italian painter
• Francesco Mancini (1830–1905), Italian painter
• Francesco Longo Mancini, Italian painter

Other

• Francesco Maria Mancini, Italian cardinal
• Francesco Mancini (composer), Italian baroque composer from Naples